Issue
Queries from one module, e.g. Database Logging (dblog), are completely overwhelming a Drupal site. No standard (and clean) ways of uninstalling the offending module are possible, due to current traffic.
Resolution
Try the command in this transcript to disable the module:
mycompany@web-3840:/var/www/html/mycompany.01live/docroot$ drush eval "\$module_data = \Drupal::config('core.extension')->get('module'); unset(\$module_data['MODULE_NAME']); \Drupal::configFactory()->getEditable('core.extension')->set('module', \$module_data)->save();" --uri=https://www.MisconfiguredSite.com(For the most common case, MODULE_NAME is dblog.)
Putting the site into maintenance mode, and fully uninstalling the module will be necessary once working the site is possible again.
Cause
The "Database Logging" module was enabled in on subsite of a large Drupal multisite, or on one site in ACSF Stack.